Given the expense of reanimation and to promote the sharing of mouse lines for the skeletal biology community, we provide here information on available mouse lines that are being actively bred in our barrier facility. The table provides an updated list of KOMP/IMPC knockout mouse lines that are being actively bred for skeletal phenotyping and will only be temporarily maintained for these purposes. Therefore, please contact us right away if you are interested in using any of these mouse lines for your research.
| Gene Symbol | Gene Name | Breeding Status |
|---|---|---|
| Alg3 | alpha-1,3- mannosyltransferase | Active |
| C57BL/6NTac | KOMP Control Line1/3/2020 | Active |
| C57BL/6NTac. X B/C2.3Ge8N10 | Col2.3GFP backbreed for KOMP | Active |
| Cdc42bpb | CDC42 binding protein kinase beta | Active |
| Cherp | Ca(2+) homeostasis endoplasmic reticulum protein | Active |
| Crcp | calcitonin gene-related peptide-receptor component protein | Active |
| Ednra | endothelin receptor type A | Active |
| Hesx1 | homeobox gene expressed in ES cells | Active |
| Il6st | interleukin 6 signal transducer | Active |
| Kif16 | Kruppel like factor 16 | Active |
| Lrp1 | low density lipoprotein receptor-related protein 1 | Active |
| Mccc2 | methylcrotonoyl-Coenzyme A carboxylase | Active |
| Meis1 | Meis homeobox 1 | Active |
| Ndc80 | Nuclear division cycle 80 | Active |
| Nup205 | nuclear pore complex 205 | Active |
| Piezo2 | piezo-type mechanosensitive ion channel component 2 | Active |
| Plod2 | procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 | Active |
| Ppfia1 | Adaptor for surface tyrosine phosphatase receptor | Active |
| Rab10 | RAB10, member RAS oncogene family | Active |
| Rbpj | recombination signal binding protein for immunoglobulin kappa J region | Active |
| Slain2 | microtubule plus-end tracking protein (+TIP) | Active |
| Slbp | stem-loop binding protein | Active |
| Slmap | sarcolemma associated protein | Active |
| Spc25 | Spindle pole body component 25 | Active |
| Stt3b | STT3 oligosaccharyltransferase complex catalytic subunit B | Active |
| Tctn3 | tectonic family member 3 | Active |
| Thsd4 | thrombospondin, type 1, domain-containing 4 | Active |
| Tm2d3 | TM2 domain containing 3 | Active |
| Tmco1 | transmembrane and coiled-coil domains 1 | Active |
| Tnnc1 | troponin C, cardiac/slow skeletal | Active |
| TRAP-tdTomato | TRAP-tomato | Active |
| Xylt1 | xylosyltransferase 1 | Active |
| Zfp706 | zinc finger protein 706 | Active |